摘要
目的对文献报道的两个合成1,1'-双环十二-2,2'-二酮方法进行了再研究.方法以环十二酮的烯胺和卤代酮反应制备标题化合物.结果合成了1,1'-双环十二-2,2'-二酮的脱水关环产物2,3,4,5-双-(邻-1,10-亚癸基)-呋喃.结论反应产物非常复杂,从中意外的获得了其关环产物.
Objective Two synthetic methods of 1, 1′-bicyclododecyl-2, 2′-dione in literature were reinvestigated. Methods The other route for 1, 1′-biscyclododecan-2, 2′-dione synthesis by the alkylation of enamine with halogenated ketone was carried out. Results The dehydration and cyclization product 2, 3, 4, 5-bis （ortho-1, 10- decylidene） furan was obtained. Its structure was confirmed by 1H, 13C NMR, ESI-MS, and IR spectral data. Conclusion The productions are very complex and unexpectedly obtained cyclization product.
出处
《河北北方学院学报（自然科学版）》
2009年第2期25-28,32,共5页
Journal of Hebei North University:Natural Science Edition
基金
国家自然科学基金资助项目(20072053)
