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米索前列醇降低产后出血疗效的临床观察

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摘要 目的探讨不同剂量的米索前列醇对减少产后出血量的影响。方法将240例第1、2产程正常的初产妇随机分为A、B、C3组,每组各80例,分别于胎肩娩出后肌内注射催产素20U,B组加用米索前列醇0.2mg舌下含化,C组加米索前列醇0.2mg舌下含化及0.2mg塞肛。比较各组产后出血量及产后出血发生情况。结果A、B、C组产后24h出血量≥500ml的发生率分别为22.5%、15.0%、10.0%,A组明显高于C组(22.5%vs10.0%,P<0.05),A与B组及B与C组分别两两比较,差异均无统计学意义(P均>0.05)。结论米索前列醇对减少产后出血量及预防产后出血安全、有效、经济、毒副作用小。
作者 陈爱华
出处 《中国厂矿医学》 2009年第2期174-174,共1页 Chinese Medicine of Factory and Mine
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