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兔皮肤和骨损伤的超微结构与损伤时间推断研究

STUDY ON THE TIMING INFERENCE OF WOUND IN RABBIT’S SKIN AND BONE
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摘要 兔小腿皮肤和骨损伤后,经1天、4天、7天、14天、21天、28天,分别用光镜及电镜进行了观察,并计算ra/fa和ccn/acn值。结果表明:①皮肤损伤后4天,纤维母细胞内浆网扩张,7天达最高峰,ra/fa为23.13%,14天后缩小;②皮肤损伤1天,即出现肌纤维母细胞,损伤4天胞浆内出现微丝束,7天~14天微丝束最多;③骨损伤切口细胞数在1天最多,ccn/acn值最高,4天和7天也较多,14天和21天下降,28天仍未降至正常。这些变化规律为损伤时间推断提供新的定量指标。 Experimental incised wounds were made on the skin and bone of rabbit’s legs under anesthesia using aseptic technique.After 1,4,7,14,21 and 28 dags,wounds were observed under light and electronic microscope,the ra/fa ratio and ccn/acn ratio were calculated.The results were as follows:(1)The endoplasmic reticulum of fibroblast expanded in 4 days after wounding,with the ra/fa ratio 23.13% at this time,and reduced 14 days after wounding.(2)The myofibroblasts appeared in l day after wounding.The microfilaments appeared in 4 days after wounding and reached a maximum gradually from the 7th to the 14th day.(3)The ccn/acn ratio at bone were the highest in lday after wounding,reduced from the 14th to the 21st day and did not drop to normal in 28 days after wounding.
出处 《温州医学院学报》 CAS 1997年第1期16-19,共4页 Journal of Wenzhou Medical College
基金 温州医学院科学基金
关键词 皮肤损伤 骨损伤 超微结构 损伤时间 skin wound bone wound light microscope ultrastructure
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参考文献3

  • 1石秋念,龚伟.损伤经过时间的实验研究[J].中国法医学杂志,1989,4(2):65-69. 被引量:3
  • 2傅晨钟,祝家镇.机械性损伤受伤时间推断的法医学研究进展[J]中国法医学杂志,1988(01).
  • 3杨增言等编写,祝家镇.法医病理学[M]人民卫生出版社,1989.

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