摘要
目的:对桑科植物广东桑Morus atropurpurea桑枝的化学成分进行研究。方法:应用硅胶、聚酰胺、Sephadex LH-20柱色谱技术进行分离纯化,并用MS和NMR分析鉴定化合物结构。结果:从95%乙醇提取物中分离得到11个化合物,分别为mulberrin(1),cyclomulberrin(2),桑白皮素(3),环桑黄酮(4),2′,4′,4,2″-tetra-hydroxy-3′-{3″-methylbut-3″-enyl-}-chalcone(5),mulberrofran G(6),东莨菪内酯(7),moruchalcone A(8),山柰酚(9),熊果酸(10),β-胡萝卜苷(11)。结论:除9,11外,其余化合物均首次从该植物中分离得到。
Objective： To study the chemical constituents of the twigs of Morus atropurpurea. Method： The compounds of the EtOAc fraction were isolated and purified by column chromatography on silica gel, polyamide, Sephadex LH -20, and their structures were elucidated on the basis of spectroscopic evidence （MS, NMR）. Result： Eleven compounds were identified as mulberrin （1）, eyclomulberrin （2）, momsin （3）, cyclomorusin （4）, 2＇, 4＇,4, 2＂-tetrahydroxy-3＇- { 3＂-methylbut-3-enyl- } -chalcone （5）, mutherrofran G （6）, scopoletin （7）, moruchalcone A （8）, kaempferol （9）, ursolic acid （10）,β-daueosterol （11）. Conclusion： Except compounds 9 and 11, all the other compounds were obtained from M. atropurpurea for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2008年第21期2499-2502,共4页
China Journal of Chinese Materia Medica
基金
广东省自然科学基金重点项目(05200575)
关键词
广东桑
黄酮
查耳酮
三萜
香豆素
Morus atropurpurea
flavonoids
chalcones
triterpenoid
coumarin
