摘要
目的观察红霉素联合莫沙比利治疗糖尿病性胃轻瘫(DGP)的临床疗效。方法将50例糖尿病性胃轻瘫患者随机分为治疗组和对照组各25例,两组均予以莫沙比利5 mg,3次/d,治疗组加服红霉素250 mg,3次/d。两组均连用4周后进行疗效评价。结果治疗后4周治疗组的症状改善总有效率88.0%,对照组的症状改善总有效率60.0%,两组总有效率比较,差异具有显著性(χ2=5.09,P<0.05),治疗组明显优于对照组。两组治疗前后胃排空时间比较,治疗组优于对照组。结论红霉素联合莫沙比利治疗糖尿病性胃轻瘫疗效明显优于单用莫沙比利。
Objective To summarize the clinical effect on combined treatment of Diabetic Gastro Paresis with erythromycin and mosabilium. Methods 50 patients with Diabetic Gastro Paresis were randomly divided into therapy group（ n = 25 ） and control group（ n = 25 ）. mosapride 5 mg three times daily for 4 weeks was given for all pantients, and erythromycin 250 mg three times daily for 4 weeks was added to therapy group. The curative effect was assessed. Results After 4 - week treatment, the total symptom improvement rate of all patients in therapy group and control group was 88.0% and 60.0%, respectively （ X^2 = 5.09, P 〈 0.05 ）, therapy group is significantly better than control group. Conclusion The clinical effects of pantoprazole combined erythromycin with mosapride on Diabetic Gastro Paresis are significantly better than those of enly mosapride.
出处
《临床和实验医学杂志》
2008年第3期40-41,共2页
Journal of Clinical and Experimental Medicine
