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利多卡因复合罗哌卡因在坐骨神经阻滞时的麻醉效果 被引量：8

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摘要 腰丛复合坐骨神经阻滞作为临床麻醉在国内外报道逐渐增多，具有许多优点，尤其对全身各系统影响轻微，而且术后有较长的镇痛时间。但坐骨神经起效时间较长是其缺点，在很大程度上阻碍了此种麻醉方式在临床上的推广应用。笔者的前期研究得出坐骨神经应用2％利多卡因联合0．75％罗哌卡因10ml时，可以加快起效时间。本研究采用2％利多卡因10ml（约1．5倍ED50）复合0．75％罗哌卡因10ml应用于坐骨神经阻滞，验证这种复合用药的临床效果和起效时间，并与传统的硬膜外阻滞比较。
作者 刘乐 郭献阳 徐旭仲 陈丽梅
机构地区 温州医学院附属第一医院
出处 《浙江创伤外科》 2008年第1期87-89,共3页 Zhejiang Journal of Traumatic Surgery
基金 浙江省科技厅资助项目(200C33015)
关键词 坐骨神经阻滞 复合用药 罗哌卡因 利多卡因 麻醉效果 起效时间 临床麻醉 硬膜外阻滞
分类号 R614.4 [医药卫生—麻醉学] R714.245 [医药卫生—妇产科学]
  • 相关文献

参考文献11

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二级参考文献26

  • 1林惠华,张威,孙晓雄.利多卡因用于坐骨神经—“三合一”阻滞的药效及药代动力学研究[J].北京医学,2005,27(1):35-38. 被引量：5
  • 2李挺,金勉,徐旭仲,卢园园.腰丛-坐骨神经阻滞应用于老年病人下肢手术[J].温州医学院学报,2005,35(5):376-378. 被引量：24
  • 3肖洁,王祥瑞,蔡美华,孙大金.盐酸罗比卡因腰丛-坐骨神经阻滞的药代动力学研究[J].临床麻醉学杂志,2005,21(11):731-733. 被引量：7
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  • 10Rooke GA, Freund PR, Jacobson. Hemodynamic response and change in organ blood volume during spinal anesthesia in elderly men with cardiac disease[J]. Anesth Analg, 199785(1): 99-105.

共引文献35

同被引文献62

  • 1刘萍,杨钰香,姚尚龙,武宙阳.臂丛神经阻滞时咪达唑仑清醒镇静的研究[J].华中科技大学学报（医学版）,2004,33(4):488-490. 被引量：3
  • 2李挺,金勉,徐旭仲,卢园园.腰丛-坐骨神经阻滞应用于老年病人下肢手术[J].温州医学院学报,2005,35(5):376-378. 被引量：24
  • 3郭献阳,徐旭仲,陈丽梅,李挺,余微萍.罗哌卡因单用及复合不同浓度利多卡因对坐骨神经起效时间的影响[J].温州医学院学报,2007,37(3):240-243. 被引量：14
  • 4曾因明,邓小明,主译.米勒麻醉学.第6版.北京:北京大学医学出版社,2006;1637-1668.
  • 5庄心良,曾因明,陈伯銮.现代麻醉学[M].第三版.北京,人民卫生出版社,2006,2505-2572.
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  • 7Enneking F K, Chan V, Greger J, et al. Lower-extremity peripheral nerve blockade : essentials of our current understanding [J]. Reg Anesth Pain Med, 2005,30(I):4-35.
  • 8Biboulet P, Morau D, Aubas P, et al. Postoperative analgesia after total-hip arthroplasty: Comparison of intravenous patient- controlled analgesia with morphine and single injection of femoral nerve or psoas compartment block, a prospective, randomized, double-blind study [J]. Reg Anesth Pain Med, 2004,29(2) : 102-109.
  • 9Campbell A, McCormick M, McKinlay K, et al. Epidural vs. lumbar plexus infusions following total knee arthroplasty: randomized controlled trial [J]. Eur J Anaesthesiol, 2008,25 (6) :502-507.
  • 10Kaloul I, Guay J, Cote C, et al. Ropivacaine plasma com'entrations are similar during continuous lumbar plexus blockade using the anterior three-in-one and the posterior psoas compartment techniques [J~. Can J Anaesth, 2004,51 ( 1 ) : 52- 56.

引证文献8

二级引证文献48

浙江创伤外科
2008年 第1期

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