摘要
目的:观察胃癌病人人体组成的特点。方法:随机选择50例拟手术的胃癌病人,健康人31例为对照组,应用双能源X线吸收法(DEXA)测定病人人体组成,同时用简易营养评价法(MNA)对胃癌病人进行营养评价。结果:男性胃癌病人较对照组脂肪量、瘦体组织量减少,分别为(15658±6481)gvs(19527±6150)g,t=2.079,P<0.05;(48727±5362)gvs(52392±5989)g,t=2.132,P<0.05;女性胃癌病人脂肪量较对照组下降(19907±4305)gvs(24145±5530)g,t=2.318,P<0.05。脂肪、瘦体组织和脂肪百分比与体质指数呈正相关(r=0.852,P<0.01;r=0.457,P<0.01;r=0.664,P<0.01)。不同营养状态的男性胃癌病人其脂肪和脂肪百分比有明显差异(F=11.184,P<0.01;F=7.986,P<0.05);不同病理分期的男性病人人体组成未见有明显差异。结论:胃癌病人人体组成变化明显,存在明显的脂肪、瘦体组织丢失,营养不良者的脂肪、瘦体组织减少更加严重,人体组成与肿瘤临床病理分期无关。
Objective： To investigate the characters of body composition of gastric cancer patients.Methods： Body composition was measured by dual-energy X-ray absorptiometry（DEXA）in 50 gastric cancer patients and 31 healthy subjects,and nutritional state was evaluated by mini nutritional assessment（MNA）.Results： Compared with control group,male gastric cancer patients showed a reduction in lean body mass and fat mass（15 658±6 481）g vs（19 527±6 150）g,t=2.079,P〈0.05;（48 727±5 362）g vs（52 392±5 989）g,t=2.132,P〈0.05,and female patients displayed a reduction in fat mass（19 907±4 305）g vs（24 145±5 530） g,t=2.318,P〈0.05.Body mass index（BMI） was positively correlated with fat mass,lean body mass and percentage of fat（r=0.852,P〈0.01;r=0.457,P〈0.01;r=0.664,P〈0.01）.There was significant difference in fat mass and percentage of fat among male patients with different nutritional status（F=11.184,P〈0.01;F=7.986,P〈0.05）.No significant difference was found in body composition of male patients at different pathologic stage.Conclusion：Gastric cancer patients have significant reduction in lean body mass and fat mass,especially the patients with malnutrition.Body composition was not connected with pathologic stage.
出处
《肠外与肠内营养》
CAS
2007年第5期286-289,共4页
Parenteral & Enteral Nutrition
关键词
胃癌
人体组成
双能源X线吸收法
简易营养评价法
Stomach neoplasms
Body composition
Densitometry,X-ray
Mini nutritionalassessment
