摘要
目的:探讨制备布洛芬片新的工艺条件,以达到中国药典1995年版新标准。方法:用适宜浓度的聚山梨酯80制粒。结果:颗粒完好,片面光洁,溶出度由原来52.86%提高到94.26%。结论:为片剂溶出度的改进提供了一种新的方法。
OBJECTIVE:To study the preparation techniques of ibuprofen tablet to meet the standard of Chinese pharmacopoeia 1995.METHODS:A proportion of polysorbate 80 was added into atom.RESULTS:Particle size was perfect and the apperance of tablet was smooth.The dissolution was improved from 52.86% to 94.26%.CONCLUSION:A new way was developed to improve the tablet dissolution.
出处
《中国药学杂志》
CAS
CSCD
北大核心
1997年第3期165-166,共2页
Chinese Pharmaceutical Journal