摘要
目的:分析掌握我院各类抗感染药的使用情况,为临床合理应用抗生素及科学制定采购计划提供依据。方法:根据我院“医院药品库存管理系统”的原始数据资料,采用限定日剂量法和销售金额排序法进行分析。结果:我院抗感染药品种数从2003年至2005年有所增加,但增幅不大,头孢菌素类品种数最多。抗感染药销售金额平均占西药销售金额的32.36%,低于国内其他医院。β-内酰胺类销售金额遥遥领先,平均占抗感染药销售金额的50.99%。青霉素类、头孢菌素类、大环内酯类、氟喹诺酮类和硝基咪唑类药物是使用频度最高的5大类,这5类药的DDDs之和平均占各年度占抗感染药物DDDs总和的85.29%。在DDDs排序前20位中,口服制剂占2/3,注射制剂占1/3;排序比>1的占75%,<1者,占25%,表明安全有效、价格低廉的抗感染药物占主导地位,临床用药基本合理。结论:掌握医院抗感染药物的应用情况,对于促进合理用药具有重要意义。
OBJECTIVE： To analyze the utilization of various anti - infectives in our hospital and to provide bases for the rational use of antibiotics in the clinic and scientific making of drug purchase plan. METHODS： The analysis was conducted using the method of defined daily use and sequence of consumption sum based on the raw data retrieved from Hospital Drug Inventory Management System. RESULTS： There was a slight increase in the kinds of anti - infectives used during 2003 - 2005, with cephalosporins showing the most in kinds. Of the total consumption sum of western drugs, the average annual consumption sum of anti - infectives accounted for 32.36 %, lower than that in the other domestic hospitals. Beta lactams antibiotics ranked far ahead of others, accounting for 50.99 % of the consumption sum of total anti - infectives. Penicilins, cephalosporins, quinolones, macrolides and nitroimidazole were the most commonly used 5 kinds, with average DDDs sum of the five kinds accounted for 85.29% of DDDs sum of total anti - infective drugs in each year. Of the top 20 drugs on the list of DDDs, the ratio of oral preparation to injections was 2 ： 1, 75 % were 〉 1 and 25 % were 〈 1 in order ratio, suggesting those anti - infectives that with low cost, safety and efficacy assumed a predominant place, and the clinical medication was rational on the whole. CONCLUSION ： The information of the use of anti - infectives is of great significance for the rational drug use.
出处
《中国医院用药评价与分析》
2007年第2期124-127,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
