摘要
目的：观察斯普林对恶性肿瘤患者化疗的辅助疗效。方法：化疗前2个周期不加斯普林，后3个-6个周期加斯普林，10ml／日，静脉点滴，每周期连用10天，从化疗第1日开始。所有患者加斯普林前后方案、剂量完全相同。结果：22例化疗患者加斯普林治疗前后外周血象及临床毒副反应有明显变化，加斯普林前WBC、PCT、HB发生Ⅰ度-Ⅲ度反应分别为72．7％、45．5％、31．7％，加斯普林后发生Ⅰ度-Ⅲ度反应分别为45．4％、40．9％、22．7％。加斯普林前神疲乏力、食欲不振、腹胀／便秘发生率为100％，加斯普林后症状好转56．2％，消失43．8％，有效率100％。结论：斯普林具有升高外周血象、改善生活质量、提高患者对化疗耐受性的作用。
Objective： To observe the effect combined spulin with chemotherapy in the patients with malignant tumour. Methods：Twenty two advanced malighamt tumour patients tvedated with four or six cycles chemotherapy, every cycle was 21 days. After 1 and 2 cyles patients were given sipulin 10ml/d,lasted 10 days. Results： All patients who were given sipulin had obvious changes in blood routine and drug effects. Before use the sipulin, WBC, PCT, HB occur Ⅰ-Ⅲ actions,in 72.7% ,45.5% ,31.7% ,patients respectively, patients not given sipulin appeared frazzle, inappetence and constipation were 100% after chemotherapy. The effective rate of sipulin in the improving symptoms of patients was 100%. Conclusion： Sipulin can improve the blood routine, life quality and tolerance of the patients with chemotherapy.
出处
《现代肿瘤医学》
CAS
2007年第2期262-263,共2页
Journal of Modern Oncology
