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血管化小鼠异位心脏移植模型 被引量：4

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摘要 啮齿动物心脏移植模型在移植免疫研究中广泛应用。其中，小鼠模型更具优势：近交系小鼠品种丰富；小鼠易于转基因、基因敲除操作；小鼠的分子生物学探针、抗体和工具药品种丰富；小鼠体重轻，对于昂贵、来源稀少的药物，小鼠模型可降低研究成本。但小鼠血管细，凝血机制活跃，容易发生动脉内膜损伤，血栓形成，导致手术失败。本研究旨在探讨小鼠心脏移植成功的影响因素。
作者 张善中 谭建明 唐孝达
机构地区 上海交通大学附属第一人民医院肾移植中心
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2006年第10期1276-1276,共1页 Chinese Journal of Experimental Surgery
关键词 心脏移植模型 近交系小鼠 血管化 异位 动脉内膜损伤 小鼠模型 分子生物学 移植免疫
分类号 R-332 [医药卫生] R654.2 [医药卫生—外科学]
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  • 1Shweiki D, Itin A, Soffer D, et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature,1992, 359:843-845.
  • 2Barleon B. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt1. Blood, 1996, 87:3336-3343.
  • 3Luster AD, Jhanwar SC, Chaganti RS, et l. Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells. Proc Natl Acad Sci USA, 1987, 84:2868-2871.
  • 4Farber JM. A macrophage mRNA selectively induced by g-interferon encodes a member of the platelet factor 4 family of cytokines. Proc Natl Acad Sci USA, 1990, 87:5238-5242.
  • 5Melder RJ. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat Med, 1996, 2:992-997.
  • 6Kim I. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule-1(VCAM-1), and E-selectin through nuclear factor-kB activation in endothelial cells. J Biol Chem, 2001, 276: 7614-7620.
  • 7Shahbazi M. Vascular endothelial growth factor gene polymorphisrns are associated with acute renal allograft rejection. J Am Soc Nephrol, 2002,13:260-264.
  • 8Semiltova N,Shen XD,Fishbein MC,et al.Posttransplant administration of allochimeric major histocompatibility complex class-Ⅰ-molecules induces true transplantation tolerance.Transplantation,2003,75:550-553.
  • 9Sebille F,Brouard S,Petzoud T,et al.Tolerance induction in rats,using a combination of anti-CD154 and donor splenocytes,given once on the day of transplantation.Transplantation,2003,75:169-172.
  • 10Sayegh MH,Perico N,Imberti O,et al.Thymic recognition of class 11 major histocompatibility complex allopeptide induces donor-specific unresponsiveness to renal allografts.Transplantation,1993,56:461-465

共引文献7

同被引文献34

  • 1俞志勇,郑树森,梁廷波,万云乐.建立小鼠异位心脏移植模型[J].浙江大学学报（医学版）,2005,34(3):271-274. 被引量：5
  • 2冯剑锷,孙宗全.应用Cuff技术建立小鼠异位心脏移植模型[J].中华实验外科杂志,2005,22(12):1576-1577. 被引量：17
  • 3Corry RJ,Winn HJ,Russell PS. Primarily vascularized allografts of hearts in mice. The role of H-2D,H-2K,and non-H-2 antigens in rejection[J].Transplantation,1973; 16(4):343-350.
  • 4野澤眞澄. 臓器移植実験マニュアル:ラット?マウスを用いた移植、虚血再灌流傷害モデル[M].秀潤社,1999:77-81.
  • 5Jiang XF,Shimaoka T,Kojo S,et al. Cutting edge:critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance[J].J Immunol,2005; 175(4):2051-2055.
  • 6Jiang XF,Kojo S,Harada M,et al. Mechanism of NKT cell-mediated transplant tolerance[J].Am J Transplant,2007; 7(6):1482-1490.
  • 7Sanna-Cherchi S,Ravani P,Corbani V,et al.Renal outcome in patients with congenital anomalies of the kidney and urinary tract.Kidney Int,2009,76:528-533.
  • 8Sargent MA.What is the normal prevalence of vesicoureteralreflux?Pediatr Radiol,2000,30:587-593.
  • 9Bailey RR.The relationship of vesico-ureteric reflux tourinary tract infection and chronic pyelonephritis-reflux nephropathy.Clin Nephrol,1973,1:132-141.
  • 10Eccles MR,Jacobs GH.The genetics of primary vesico-ureteric reflux.Ann Acad Med Singapore,2000,29:337-345.

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中华实验外科杂志
2006年 第10期

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