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游离脂肪酸升高相关因素分析 被引量:5

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摘要 目的:探讨与血清游离脂肪酸升高的相关因素,为进一步研究游离脂肪酸升高与某些疾病的相关关系提供依据。方法:检测108例游离脂肪酸升高的病人肝功能、肾功能、血脂和血糖指标。结果:FFA升高与5项肝功能指标:ALT、AST、T-Bil、D-Bil、TBA极显著相关(P≤0.01),与肾功能指标中的UA呈极显著相关(P≤0.01)。结论:探讨游离脂肪酸升高对肝脏疾病、脂代谢异常和肾病有重要意义。
作者 伍树芝
出处 《中国医药指南》 2006年第6期68-69,共2页 Guide of China Medicine
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  • 1周仲医.2型糖尿病患者血尿酸水平的结果分析[J].职业卫生与病伤,2004,19(2):105-106. 被引量:3
  • 2[1]Hu FB, Dam V, Liu S. Diet and risk of type Ⅱ diabetes: the role of types of fat and carbohydrate. Diabetologia, 2001,44:805-817.
  • 3[2]Tang Y, Osawa H, Onuma H, et al. Phosphodiesterase 3B gene expression is enhanced in the liver but reduced in the adipose tissue of obese insulin resistance db/db mouse. Diabetes Res Clin Pract, 2001, 54: 145-155.
  • 4[3]Yoshikawa H, Tajiri Y, Sako Y, et al. Effects of free fatty acids on β-cell functions: a possible involvement of peroxisome proliferators-activated receptors α or pancreatic/duodenal homeobox. Metabolism, 2001, 50: 613-618.
  • 5[4]Mu YM, Yanase T, Nishi Y, et al. Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells. Endocrinology, 2001, 142: 3590-3597.
  • 6[5]Lu ZH, Mu YM, Wang BA, et al. Saturated free fatty acids,palmitic acid and stearic acid, induce apoptosis by stimulation of ceramide generation in rat testicular Leydig cell. Biochem Biophy Res Commun, 2003, 303: 1002-1007.
  • 7[6]Unger RH, Zhou YT. Lipotoxicity of beta-cells in obesity and other causes of fatty acid spill over. Diabetes, 2001, 50(Suppl 1): S118-S121.
  • 8[7]Yu C, Chen Y, Cline GW, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1(IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem, 2002, 277: 50230-50236.
  • 9[8]Tripathy D, Mohanty P, Dhindsa S, et al. Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes, 2003, 52: 2882-2887.
  • 10[9]Burke JR. Targeting I kappa B kinase for the treatment of inflammatory and other disorders. Curr Opin Drug Discov Devel,2003, 6: 720-728.

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  • 1Han, Ping,Zhang, Yong-Yan,Lu, Yan,He, Bing,Zhang, Wei,Xia, Fei.Effects of different free fatty acids on insulin resistance in rats[J].Hepatobiliary & Pancreatic Diseases International,2008,7(1):91-96. 被引量:10
  • 2米杰,张力.胰岛素抵抗[J].中华预防医学杂志,2004,38(4):225-225. 被引量:3
  • 3王丽霞,郑明学.细胞凋亡的调控与检测[J].畜牧兽医杂志,2007,26(2):40-42. 被引量:4
  • 4曾爱源,蒋静子,唐永刚,刘开祥.血清脂蛋白a、纤维蛋白原、D-二聚体水平与急性缺血性脑卒中患者的相关分析[J].实用心脑肺血管病杂志,2007,15(5):348-350. 被引量:10
  • 5杨文正动物矿物质营养[M]北京:中国农业出版社,1996145-146.
  • 6Chen H,Xing B ,Liu X,et a/.Ozone oxidative preconditioning inhibits inflammation and apoptosis in a rat model of renal ischemia/reperfusion injury [J].European Journal of Pharmacology, 2008,581 : 306 - 314.
  • 7Duan W,Li X,Shi J,et a/.Mutant TAR DNA-binding protein-43 in- duces oxidative injury in motor neuron-like cell [J].Neuroscience, 2010,169 : 1621 - 1629.
  • 8Krueger A,Baumann S,Krammer P H.Flice inhibitory proteim:P,.egula- tors of death receptor mediated apoptosis [J].Molecular and Cellular Biology, 2001.21:8247 - 8254.
  • 9Li J,Xia X,Ke Y,et a/.Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways [J]. Biochimic et Biophysica Acta, 2007,1770 : 1169 - 1180.
  • 10Li N,Li Q,Qian Z,et aLlmpaired TLR.3/IFN-beta signaling in mono- cyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure:relevance to the severity of liver damage[J].Biochemical and Bio- physical Research Communications, 2009,390 : 630 - 635.

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