摘要
目的：观察化疗药物经支气管动脉灌注肺癌的疗效。材料与方法：收集化疗药物经支气管动脉灌注原发性肺癌118例，其中中央型78例，周围型40例；鳞癌52例，腺癌33例，大细胞未分化癌19例，小细胞未分化癌14例。观察其组织学类型、血供情况及发生部位与疗效的关系。结果：小细胞未分化癌总缓解率为78．6％，鳞癌75．0％，腺癌63．6％，大细胞未分化癌57．0％，中央型与周围型总缓解率分别为71．4％和52．3％；多血供型与中等血供型总缓解率为74．2％。而少血供型仅为23．5％。结论：化疗药物经支气管动脉灌注是治疗肺癌的有效方法；疗效主要取决于癌瘤血供癌细胞对抗癌药物的敏感及／与癌瘤细胞学类型。
Purpose: To observe effectiveness of lung cancer responsed to bronchial arterial infusion(BAI) of anticancer drugs. Meterials and methods: BAI were performed in 118 patients with primary lungcancer, including the type of central tumors in 78 cases, the type of the lung periphery in 40 cases; squamouscell carcinoma in 52 cases, adenocarcinoma in 33, large cell undifferentiated carcinoma in 19, small cell undif-ferentiated carcinoma in 14. Relationsipe between effetiveness responsed to BAI and lung cancer's patholo-gy, blood provision and position were observed. Results: The response rate of small cell undifferentiated car-cinoma was 78. 6%, squamous 75. 0%, adenocarcinomas 63. 6%, large cell undifferentiated 57. 0%; the re-sponse rate of the central tumors and the lung periphery were seperately 71. 4% and 52. 3%; the responserate of more and middle blood provision was 74. 2%, but less blood provision was 23. 5% Conclusion: BAIhad satis factory effectiveness in the treatment of the primary lung cancers; the effectiveness was decided bythe blood provision of cancer, the sensibility of cancer cells responsed to anticancer drugs and lung cancer's pathology.
出处
《现代医用影像学》
1996年第3期114-117,共4页
Modern Medical Imageology
关键词
肺肿瘤
癌
介入放射学
支气管动脉灌注
Lung cancer Interventional radiology Bronchial arterial infusion
