摘要
目的研究三氧化二砷对中晚期原发性肝癌的疗效。方法治疗中晚期原发性肝癌共25例,单药三氧化二砷注射液10 mg,静脉滴注,1次/d,连用10 d为一周期,间歇2周重复。结果PR 4例,NC 17例,PD 4例,缓解率为16.0%。主要的不良反应为消化道反应、骨髓抑制及肝功能改变。结论三氧化二砷治疗原发性肝癌有效,且不良反应少,值得临床推广。
Objective To study the efficacy of arsenic trioxide （Aa203 ） in treating primary liver cancer. Methods Twenty-five patients with advanced primary liver cancer were treated with As2O3 injection only at a dose of 10 mg/day by intravenous instillation for succesive 10 days and the treatment was repeated after 2 weeks. Results The response rate was 16.0% with 4 cases PR, 17cases NC and 4 cases PD. The major adverse reactions were mild G-I reaction, mild bone marrow suppression and hepatic fuctional damage. Conclusion As2O3 injection is effective in treating primary liver cancer and the adverse reactions are mild, so it is worthy of popularization.
出处
《中国肿瘤临床与康复》
2006年第3期232-233,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
肝肿瘤/药物疗法
三氧化砷
Liver neoplasms/drug therapy
Arsenic trioxide
