摘要
目的:探讨超声组织定征在不同剂量有机磷中毒兔肾脏改变中的价值。材料和方法:建立兔有机磷中毒模型,分别于染毒后1h、3h对4个不同剂量实验组及对照组行二维超声及背向散射积分(IBS)检查。二维超声观察肾脏的回声,测量肾脏的大小,IBS定量分析肾脏改变。结果:任一剂量组染毒后肾脏回声均无改变。随着剂量的增大、染毒时间的延长,肾脏体积、长径与对照组相比差异均有统计学意义(P<0.05),体积的变化早于长径。染毒1h后,肾脏皮质及髓质IBS%与对照组相比,组3、组4差异有统计学意义(P<0.05);染毒3h后,肾脏皮质及髓质IBS%与对照组相比,组2、组3、组4差异有统计学意义(P<0.05)。结论:超声组织定征可以为不同染毒剂量有机磷类化合物中毒兔肾脏改变提供依据。
To explore the value of ultrasonic tissue characterization of kidney with different dosage in organophosphorus poisoning rabbits. Materials and Methods： Rabbit models of organophosphorus poi- soning were established. Ultrasonic examinations were performed on four different dosage experimental groups and control group at the time 1 h and 3 h after rabbits being poisoned. The echo and the size of kidney were evaluated by two - dimensional ultrasound. The changes of parenchyma were quantitatively analyzed by IBS. Results： No significant changes were found in kidney echo of any groups. With the increasing dosage and prolonging time of poisoning, significant changes were found in volume and length of kidneys compared with that in control group（P 〈 0.05） . The change of volume emerged earlier than length did. There is significant difference in IBS% of both cortex and medulla in group 3 and 4 compared with that in control group after 1 h the rabbits were poisoned（P〈0.05）. There is significant difference in IBS% of both cortex and medulla in group 2, 3 and 4 compared with that in control group after 3 h the rabbits were poisoned（P〈0.05）. Conclusion： Useful evidence can be offered by ultrasonic tissue characterization for changes of kidney in different dosage in organophosphorns poisoning rabbits.
出处
《中国医学计算机成像杂志》
CSCD
2006年第2期136-138,共3页
Chinese Computed Medical Imaging
关键词
兔
肾
超声组织定征
有机磷中毒
Organophosphorus poisoning Rabbit Kidney Ultrasonic tissue characterization
