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结节性硬化症脑部CT和MRI表现(附12例报告) 被引量:8

CT and MRI Findings of Cerebral Tuberous Sclerosis Complex
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摘要 目的:分析结节性硬化症脑部CT和MRI表现,以提高对本病的认识。方法:回顾性分析12例经临床证买为结节性硬化症患者的CT和MRI脑部影像学表现。结果:TSC脑部主要影像学改变包括:①室管膜下结节(12例),CT 上表现为多发高密度钙化结节,MRI上表现为T1WI高信号、T2WI低信号7例,T1WI和T2WI上均为低信号1例,T1WI 上呈等信号、T2WI上呈低信号4例;②皮层及皮层下结节(9例),其CT表现为高密度钙化灶3例、低密度灶6例,MRI上呈T1WI低信号、T2WI高信号9例;③脑白质异常(6例),CT上表现为多发低密度灶4例,MRI上表现为T1WI低信号、 T2WI高信号6例。5例行MRI增强扫描,示室管膜下结节呈中等强化,皮层及皮层下结节和脑白质异常信号均未见强化。结论:CT和MRI能较好显示结节性硬化脑部改变,CT对显示钙化结节较敏感,MRI对显示皮层及皮层下结节和脑白质改变较敏感。 Objective:To study the CT and MRI findings of cerebral tuberous sclerosis complex. Methods:The CT and MRI features of 12 cases of clinically diagnosed cerebral tuberous sclerosis complex were restrospectively analysed. Results: The main findings of imaging examinations were as follows:① subependymal nodules (n = 12), with multiple calcification shown on CT (n= 12) ,high signal intensity on T1WI and low signal intensity on T2WI (n= 7) ,low signal intensity on both T1 WI and T2 WI (n= 1) ,iso-signal intensity on T1 WI and low signal intensity on T2 WI (n= 4) shown on MRI; ② Cortical and subcortical tubercle (n= 9). CT showed calcification in 3 cases and low density in 9 cases;MRI showed low signal intensity on T1 WI and high signal intensity on T2 WI in 6 cases; ③ White matter lesion (n= 6). Low density lesions were displayed on CT in 4 cases. MRI showed low signal intensity on T1 WI and high signal intensity on T2 WI in 6 cases. On 5 cases which had contrast enhanced MRI,all of the subependymal nodules were moderately enhanced, but no enhancement was demonstrated on cortical tubers and white matter lesions. Conclusion:CT and MRI are sensitive to the cerebral changes in tuberous sclerosis complex and CT is more sensitive in showing calcified nodules, MRI is more sensitive in revealing cortical tubers and white matter lesions.
出处 《放射学实践》 2006年第1期30-33,共4页 Radiologic Practice
关键词 结节性硬化 磁共振成像 体层摄影术 X线计算机 Tuberous sclerosis Magnetic resonance imaging Tomography,X-ray computed
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