摘要
介绍了5-甲氧基吲哚在药物合成中的重要用途,叙述了5-甲氧基吲哚的主要合成方法,采用了以吲哚为原料,经2-磺酸钠-1-乙酰基-二氢吲哚半水合物和5-溴吲哚中间体的合成路线,合成了标题化合物5-甲氧基吲哚。产品进行了纯化和结构鉴定。产品纯度达98%以上,反应总收率50%以上。
The important use and several main methods to synthesize 5-methoxy-indole of 5-methoxyindole in synthesis medication are described. 5-methoxy-indole was preparated using synthesis course from the indole via sodium 1-acetylindole-2-sulfonate hemihydrate,and 5-bromoindole intermediates,The product is purified and determined. All yield over 50%,product purity over 98%.
出处
《精细化工中间体》
CAS
2005年第6期27-28,40,共3页
Fine Chemical Intermediates
