摘要
目的观察中医健脾化湿散瘀方与血脂康合用对乙肝后脂肪肝患者血脂和肝功能的影响。方法将107例乙肝后脂肪肝患者随机分为两组,治疗组62例,以健脾化湿散瘀方为主,加服血脂康胶囊2粒,每日2次;对照组45例,只服用血脂康胶囊2粒,每日2次,两组均8周为一个疗程。观察血脂[TCTGHDLCLDLCApoA1ApoBLP(a)]、肝功能(ALTASTCHE)的变化。结果上述两组经治疗后均能显著降低TCLDLCApoB水平,组间无明确显差异(P>0.05),但治疗组降TG,升高HDLCApoA1的作用明显优于对照组(P<0.05)。此外,治疗组治疗后ALTASTCHE明显改善,与治疗前比较有显著性意义(P<0.01)。结论健脾化湿散瘀方与血脂康合用对乙肝后脂肪肝的血脂、肝功能有明显的改善,疗效优于单用血脂康。
To examine the impact of Jianpihuashisanyu Fang and Xuezhikang recipe on the serum lipids and liver function in patients with chronic hepatitis B （CHB） and fatty liver. Method： 107 patients with chronic hepatitis B and fatty liver were treated for 8 weeks and randomly divided into two groups： the research group has 62 patients treated by Jianpihuashisanyu Fang and Xuezhikang recipes （bid） ; the control group has 45 patients treated by Xuezhikang recipes （ bid）. The serial indices of serum lipids （ including TC, TG, HDL-C, LDL-C, ApoA1, ApoB, LP（a） ）, and the liver function （including ALT,AST,CHE）were tested. Results The level of TC,LDL-C and ApoB were samely decreased in two groups （P〉0.05） ,but the level of TC in research group was significantly lower than that of the control（P〈0.05） ,the level of HCL-C and Apo A, in research group was significantly higher than that of the control （P〈0.05）. In research group,the ALT,AST and CHE were significantly decreased to the normal level（ P〈0.01 ）. Conclusion： Effect of the treatment of Jianpihuashisanyu Fang and Xuezhikang recipe on CHB with fatty liver is significantly better than treated by Xuezhikang recipe only.
出处
《中国实验方剂学杂志》
CAS
2005年第5期67-69,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
健脾化湿散瘀方
乙肝后脂肪肝
血脂
肝功能
Jianpihuashisanyu Fang
CHB with fatty liver
serum lipid
liver function
