摘要
用抗Ｓ－１００蛋白、ＣＤ４５ＲＯ和ＣＤ２０等抗体对３３例口腔扁平苔藓病灶中郎格罕氏细胞（ＬＣ）、Ｔ淋巴细胞和Ｂ淋巴细胞进行免疫组化染色并计数。结果表明ＬＣ在病变内比在正常粘膜中明显增多。国有层带状浸润的淋巴细胞中Ｔ淋巴细胞占优势（９８．８３％），这些浸润的淋巴细胞与ＬＣ有密切关系。提示ＬＣ作为抗原提呈细胞在口腔扁平苔藓病变的发生、发展和持续过程中起着关键作用，同时又成为靶细胞受到Ｔ淋巴细胞的攻击而损伤。
Abstract Langerhan's cells (LC) , T and B lymphocytes of 33 cases with oral lichen planus (OLP) were immunohistochemical stained and numbered by S-100 protein, CD45RO and CD20.The results showed that LC in OLP were much more than LC in oral mucosa.T lymphocytes in the densely infiltrated lymphocytes of subepithelium were preponderant (98.83%) .These infiltrated lymphocytes had close relation with LC. It is suggested that, considered to be antigen-presenting cells, LC might play an important role in arising and development of OLP.on the other hand as target cells, LC were injured by T lymphocytes.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1995年第1期22-23,35,共3页
West China Journal of Stomatology
基金
广西医科大学附属口腔医院科研经费资助
