摘要
目的:探讨口服辛伐他汀早期治疗不稳定性心绞痛(UAP)对血脂及缺血事件发生的影响。方法:85例UAP 患者被随机分为治疗组(常规治疗外加服辛伐他汀,44例)和对照组(仅常规治疗,41例),于治疗前,治疗后6个月观察血脂水平及缺血事件发生率。结果:①对照组治疗前、后血脂水平无显著性变化(P>0.05),治疗组治疗后血脂水平明显下降(P<0.05);②治疗组的缺血事件明显少于对照组(P<0.05)。结论:辛伐他汀可明显降低不稳定型心绞痛患者血脂水平及缺血事件发生率。
Objective:To evaluate the efficacy of simvastatin early treatment of patients with unstable angina pectoris (UAP). Methods: Eighty-five subjects were randomly divided into simvastatin group and control group. They all underwent blood lipid monitoring and observation of ischemic events before therapy and six months after therapy. Results:Compared with the baseline values, after six months treatment, there was a significant reduction of blood lipid levels in simvastatin group (P<0. 05), but without statistic difference in control group (P>0. 05). During the six months of follow-up, fewer ischemic events occurred in the simvastatin group (P<0. 05). Conclusion: Simvastatin can significantly reduce blood lipid levels and the incidence of ischemic events.
出处
《心血管康复医学杂志》
CAS
2005年第2期137-139,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
