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鼻NK/T细胞淋巴瘤31例临床分析 被引量:3

Analysis of clinical manifestations in nasal NK/T cell lymphomas
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摘要 目的探讨鼻NK/T细胞淋巴瘤的临床特征和病理特点,以便提高其临床诊断和治疗水平。方法对我科1991 -2001年收治的31例患者均行病理或病理加免疫组化检查,分别采用单纯放疗或放疗加全身化疗等治疗方法。结果随访1 -10年, 15例患者达到完全缓解, 48. 4%; 5例患者达到部分缓解, 16. 1%; 11例患者病情进展, 35. 5%。其中死亡7例, 22. 6%。结论鼻NK/T细胞淋巴瘤的恶性程度高,应首选综合治疗方法。 Objective To investigate the clinical findings, histopathological features, treatment outcome of NK/T cell lymphomas and to improve the diagnosis and treatment of the tumor. Method From 1991 to 2001 , there were thirty one nasal NK/T cell lymphomas patients treated in our department, five patients were treated with only radiotherapy, twenty six patients were treated combination radiotheraphy with chemotherapy, and all patients were followed up for 1-10years. Result Fifteen patients completely alleviated, five patients partial alleviated, eleven aggravated and seven died. Conclusion Nasal NK/T cell lymphomas appear to have a male predominance. The combination therapy for it is the optimal at present.
作者 王轶 周天明
出处 《川北医学院学报》 CAS 2005年第1期28-30,共3页 Journal of North Sichuan Medical College
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  • 1刘丹丹,王忠植.鼻及鼻型结外血管中心性T/NK细胞淋巴瘤—定义、鉴别诊断和流行病学[J].国外医学(耳鼻咽喉科学分册),2000,24(5):288-291. 被引量:8
  • 2Jaffe ES, Chan JK, Su I J, et al. Report of the Workshop on Nasal and Related ExtranodalAngiocentric T/Naturel Killer Cell Lymphomas. Definitions, differential diagnosis,and epidemiology. Am J Surg Pathol,1996,20: 103-111.
  • 3Takahashi N, Miura I, Chubachi A, et al. A clinicopathological study of 20 patients with T/natural killer (NK)-cell lymphoma-associated hemophagocytic syndrome with special reference to nasal-type NK/T-cell lymphoma. Int J Hematol, 74:303-308.
  • 4Logsdon MD, Ha CS, Kavadi VS, et al. lymphomas of paranasal sinuses: improved outcome and altered prognostic factors with combined modality therapy. Cancer, 1997,80: 477-488.

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