摘要
82例胃癌侵袭部位肥大细胞的分布情况观察结果表明:肿瘤侵袭部位肥大细胞数量与肿瘤组织学类型、粘液性质无关,但与浸润深度及局部淋巴结的有无转移有关。肿瘤侵袭部位肥大细胞数量越多,癌组织在胃壁浸润就越深,局部淋巴结内转移就越容易发生。提示,肿瘤侵袭部位肥大细胞在胃癌的浸润和转移中可能起一定的促进作用。
The distribution of mast cells at sites of tumor invasion in 82 gastric carcinomas was studied.The results showed that the relationship between numbers of mast cells at tumor invasion and histological types,mucous character was not evident,but numbers of mast cells at tumor invasion were strongly associated with infiltrating depth and metastatic condition of local lymph nodes of the gastric carcinomas.The numerouser was the mast cell at tumor invasion,the deeper was the infiltrating depth of cancer tissues in gastric wall,and the commoner was the local lymph node metastasis.Our observation indicated that the mast cells at sites of tumor invasion played probably a promotive role in infiltration and metastasis of gastric carcinomas.
作者
熊永炎
曾俊
李蓓芸
唐志佼
王敏
Xiong Yongyan;Zeng Jun;Li Peiyun(Department of Pathology,Hubei Medical University,Wuhan 430071,China)
关键词
胃肿瘤
肿瘤转移
肥大细胞
浸润
stomach neoplasms
neoplasm invasiveness
mast cells
neoplasm metastasis