摘要
目的 探讨慢性乙型肝炎 (HB)与非慢性HB患者的胆囊组织中HB病毒的感染情况。方法 应用PCR技术对慢性HB、非慢性HB的石蜡包埋胆囊标本进行乙型肝炎病毒 (HBV)DNA检测 ,结果HBVDNA阳性率分别为 5 8.8% (2 0 / 34)、17.1%(6 / 35 )。在HBVDNA阳性病例中胆石症检出率分别为 6 0 % (12 / 2 0 )、16 .6 % (1/ 6 )。结论 胆囊组织中确实含有HBV感染 ,慢性HB感染率高 ,而且慢性HB与胆石症发病率有关。
Objective To discuss infection status of HBV in gallbladder tissues of chronic and non-chronic HB patients.Methods The paraffin embedded gallbladder samples of chronic hepatitis B patients and non-chronic hepatitis B patients were investigated by using PCR assay.Results HBV DNA were found in gallbladder samples of chronic HB patients(58.8%),significantly higher than that of gallbladder samples of non-chronic HB patients (17.1%), in the cases of HBV DNA positive rate of gallstone in samples of chronic HB patients (60%) and in samples of non-chrowith HB patients (16.6%).Conclusion There is HBV in the gallbladder tissues,with high infection rate in chronic HB related to cholelithasis.
出处
《中国血液流变学杂志》
CAS
2004年第3期372-373,共2页
Chinese Journal of Hemorheology
