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Microcalorimetric Study of the Effect of Porphyrin-Cholesterol Esters on Cancer Cells HL-60

Microcalorimetric Study of the Effect of Porphyrin-Cholesterol Esters on Cancer Cells HL-60
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摘要 By using an LKB-2277 Bioactivity Monitor, the effect ofporphyrin-cholesterol esters on cancer cells RL-60 were examined at 25℃.There is a dirrerence in the shape of the thermogenesls curve samong different kinds or Porphyrln-cholesterol esters,and the death rate or HL-60 cells is also different. The results show that porphyrin-chsterol esters can powerfully inhibit their metabolism, the inhibitory sequence is Ⅱ >I >Ⅲ,but the inhibitory way of each ester is different. By using an LKB-2277 Bioactivity Monitor, the effect ofporphyrin-cholesterol esters on cancer cells RL-60 were examined at 25℃.There is a dirrerence in the shape of the thermogenesls curve samong different kinds or Porphyrln-cholesterol esters,and the death rate or HL-60 cells is also different. The results show that porphyrin-chsterol esters can powerfully inhibit their metabolism, the inhibitory sequence is Ⅱ >I >Ⅲ,but the inhibitory way of each ester is different.
出处 《Wuhan University Journal of Natural Sciences》 CAS 1996年第2期235-238,共4页 武汉大学学报(自然科学英文版)
关键词 Porphyrin-cholesterol ester Cancer cells HL-60 Microcalorimetric method THERMOCHEMISTRY Porphyrin-cholesterol ester,Cancer cells HL-60,Microcalorimetric method,Thermochemistry
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