摘要
To the Editor:By a randomized controlled trial,Xi et at[1]assessed the effects of edaravone on the development of postoperative delirium(POD)and perioperative neurocognitive disorders(PND)in elderly patients with hip replacement and showed that edaravone significantly decreased the incidence of POD within 7 days after surgery and the incidences ofPNDat 1 and 12months after surgery.Given that both PODand PND are common complications after hip surgery in elderly patients and have been significantly associated with postoperative death,hospital-acquired complications,persistent cognitive impairments,poor postoperative functional recovery,prolonged duration of hospital stay,and increased healthcare costs,[2,3]their findings have potential implications.However,we noted several issues of this study on which we would like to invite authors’comments.
